Molindone Monohydrochloride

《英文msh詞典》Molindone Monohydrochloride
[入口詞] Molindone Monohydrochloride
[主題詞] Molindone
[藥動學] Antipsychotic Agents
[英文釋義] An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual,1994,p283)